KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XRCC1
All Species:
22.12
Human Site:
T358
Identified Species:
48.67
UniProt:
P18887
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18887
NP_006288
633
69526
T358
P
D
W
T
R
D
S
T
H
L
I
C
A
F
A
Chimpanzee
Pan troglodytes
XP_512717
596
65689
Y333
A
F
A
N
T
P
K
Y
S
Q
V
L
G
L
G
Rhesus Macaque
Macaca mulatta
XP_001100256
645
69984
R397
G
A
V
T
G
K
P
R
G
E
G
T
E
P
R
Dog
Lupus familis
XP_533653
654
71801
T379
P
D
W
T
P
D
S
T
H
L
I
C
A
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q60596
631
68952
T358
P
D
W
T
P
D
S
T
H
L
I
C
A
F
A
Rat
Rattus norvegicus
Q9ESZ0
631
68817
T358
P
D
W
T
P
D
S
T
H
L
I
C
A
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516926
549
59237
I310
V
L
S
R
G
G
R
I
V
R
K
E
W
V
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080711
651
73244
T359
P
D
W
T
P
D
S
T
H
L
I
C
A
F
A
Zebra Danio
Brachydanio rerio
NP_001003988
615
68071
T360
P
D
W
T
P
D
A
T
H
L
I
C
A
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572217
614
68751
K349
K
S
T
A
K
E
E
K
E
Q
L
R
K
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180271
512
56847
Y272
A
F
A
N
T
P
K
Y
N
Q
V
K
G
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
82.3
86
N.A.
86
86.5
N.A.
47.7
N.A.
53.9
51.1
N.A.
20.7
N.A.
N.A.
38.8
Protein Similarity:
100
94.1
83
88.3
N.A.
91.1
91
N.A.
56.5
N.A.
67.7
68.8
N.A.
36.9
N.A.
N.A.
55.1
P-Site Identity:
100
0
6.6
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
93.3
86.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
6.6
6.6
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
93.3
93.3
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
19
10
0
0
10
0
0
0
0
0
55
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
0
% C
% Asp:
0
55
0
0
0
55
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
10
0
10
10
0
10
10
10
10
% E
% Phe:
0
19
0
0
0
0
0
0
0
0
0
0
0
55
0
% F
% Gly:
10
0
0
0
19
10
0
0
10
0
10
0
19
0
19
% G
% His:
0
0
0
0
0
0
0
0
55
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
55
0
0
0
0
% I
% Lys:
10
0
0
0
10
10
19
10
0
0
10
10
10
10
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
55
10
10
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
55
0
0
0
46
19
10
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
10
10
0
10
0
10
0
0
10
% R
% Ser:
0
10
10
0
0
0
46
0
10
0
0
0
0
0
0
% S
% Thr:
0
0
10
64
19
0
0
55
0
0
0
10
0
0
0
% T
% Val:
10
0
10
0
0
0
0
0
10
0
19
0
0
10
0
% V
% Trp:
0
0
55
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _